In sustained-release (SR) or extended-release (ER) formulations, the relationship between Tmax, Cmax, and dissolution specification time points is critical to ensure the product delivers the drug at a controlled rate, maintaining therapeutic levels over an extended period. Unlike immediate-release formulations where the goal is rapid absorption and a quick Tmax, SR products are designed to…
In pharmaceutical development, a drug’s success depends not only on its formulation but also on how efficiently it reaches the bloodstream. One of the most critical yet often overlooked factors? Dissolution testing and its direct impact on pharmacokinetics (PK). What’s a Dissolution Profile? Dissolution testing simulates how a tablet releases its active ingredient in the…
Clinical pharmacy is a specialized branch of pharmacy that focuses on patient care and the optimization of medication therapy. It involves working directly with patients and healthcare providers to ensure safe, effective, and appropriate use of medications. Within clinical pharmacy, there are several sub-branches or areas of specialization. Here are the key branches of clinical…
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